The list is not just skewed toward bioinformatics; a majority of them is bioinformatics software. I would not call BioPerl or HTSeq high-performance-computing software. Some of the software are written by academic programmers with all attendant baggages. I am not aware of any bioinformatics software written in Fortran, which is not popular in the bioinformatics community. But this is not to say Fortran might not be a good fit. The Broad Institute is rewriting some of its tools in C++ with help from Intel to leverage vector instructions. Who is to say if they had started with Fortran they might not have gotten vector instructions for free earlier.