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Which is interesting because of the SSRI I'm on all MDMA did was make me grind my teeth really bad. I want to try it again but don't want to stop the SSRI to do so.


You took MDMA while on an SSRI? You really should research a drug's mechanism of action and how multiple drugs may interact before taking them together.

Im not a medical professional, I just want to give you a quick overview so you don't repeat that mistake. Do your own research.

- An SSRI (Selective Serotonin Re-uptake Inhibitor) blocks your brain's re-uptake of serotonin and effectively increases your brain's levels of serotonin.[1]

- MDMA acts as a presynaptic releasing agent of serotonin. Increasing the amount of serotonin in the synaptic cleft (space between neurons).[2]

- That means the two of these drugs combined can cause a huge spike in serotonin and potentially lead to serotonin syndrome (toxicity).

Be safe.

[1] https://en.wikipedia.org/wiki/Selective_serotonin_reuptake_i...

[2] https://en.wikipedia.org/wiki/MDMA


This can also cause serotonin syndrome, which can cause serious damage to your brain and untreatable side effects. Not a safe combination.


From my understanding, SSRI's negate the effects of MDMA. So you can't do both.

https://www.erowid.org/chemicals/mdma/mdma_info9.shtml


Using MDMA and and SSRI together is a bad combination.

https://www.erowid.org/chemicals/mdma/mdma_info9.shtml


I was never on a SSRI for my depression. For many reasons, the biggest one being that I was way too broke to see a doctor and get a prescription during a lot of that point in my life, never mind pay for it.




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