I run privoxy locally on OSX and I like that it runs in a separate process (AB+ with a few dozen tabs open really sucks up RAM) and blocks ads on other things too (twitter clients come to mind) when set up as a system proxy. It's not the most straightforward thing to configure, but once you figure it out it's pretty great. I've never seen it donk up my pages like some of the old proxies used to; this stuff has come a long way in the past decade.

There are also a few scripts around that will fetch AB+-format lists and convert them into privoxy lists. Here's a decent intro: https://wiki.archlinux.org/index.php/privoxy

Also https://hackage.haskell.org/package/adblock2privoxy

On a router: http://blog.vanutsteen.nl/2014/01/05/installing-privoxy-with...