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Maybe I'm missing some history, but I don't think that Bayer ever wanted to enter that market. He doesn't want to do business in India.

This basically says that if you aren't in the Indian market or aren't offering your product for a price that India agrees with, your IP protection is meaningless.

This starts to get murky from an ethical point of view because we are talking about a cancer medication, and I doubt that software IP would fall under the compulsory licensing. But, cancer drugs are expensive to develop. Bayer should absolutely be afforded some IP protection to recoup the costs of developing the drug. Otherwise, they'll just stop; or more likely, just increase the prices elsewhere around the world.

I'm sure that Bayer isn't as concerned with losing the Indian market for the drug. But rather, they should be more worried about the Indian generic version of the drug hitting the international market.




> This basically says that if you aren't in the Indian market or aren't offering your product for a price that India agrees with, your IP protection is meaningless.

That seems reasonable. Why should we expect India to grant privileges to a company that wants nothing to do with India? They are giving India no reason to give a shit.

If Bayer has an issue with Indian generics getting into countries that it does have an interest in doing business in, then Bayer can appeal to those countries to block the import of those generics.


" or more likely, just increase the prices elsewhere around the world."

Are you saying they will make more money by increasing prices around the world? If so, why wouldn't they do that regardless of India's decision? They basically ignore supply/demand curves until India makes them angry? Or are you making some weird argument where they have to raise their prices in the face of medical tourism as opposed to the lowering everyone usually assumes?


Let's say the drug cost $1 billion to develop (factoring all of the other drugs that failed that they also need to pay for). Now they price that out so that they can recoup that $1 billion over the lifetime of the patent, plus a reasonable profit (remember these are public companies). Let's say that they want to sell the drug in India, and expect to get $50 million out of that market.

Now, since India is no longer a market for the drug, the amount of money that Bayer needed to make from India needs to be made from the rest of the world. That's $50 million more that the rest of the world will need to spend to subsidize India.

Even worse - what happens if the Indian generic form of the drug hits the international market? Now Bayer needs to recoup even more from the remaining international patients/insurance.

Or, what happens if patients from wealthier countries start going to India for treatment instead of staying home? Even more that Bayer needs to charge the rest of the world.

They need to make a profit to finance their next drugs in their pipeline.

The cost savings in medical tourism are usually attributed to lower labor and facility costs, not necessarily cheaper drugs.


Sorry no. They don't price things so they can recoup a fixed amount + a reasonable profit. Do you really think they say hmm we could price it a little higher and make more but we'll just stick to a reasonable profit. Likewise do you think consumers say, wow they spent a billion dollars developing this, therefore I am willing to pay them ($1 billion + 20% reasonable profit)/(total number of units sold)? That's not how supply and demand works. Drug companies price it to make the most on it regardless of any sunk costs. Why would thyley choose to make more or less money based on whether they are currently angry at India? They will always choose more or the shareholders can actually sue the board for abandoning their interests.


Over the long term... yes, they do try to recoup the costs of developing a drug and a reasonable profit. I was deliberating simplifying things.

Over the short term, the costs of developing a drug are a sunk cost that has already been financed using the profits from the previous round of drugs. They try to get as much out of the market as they can with their current lineup of drugs so that they can pay for the pipeline that is developing the next round. Over the long term over many drugs on the market, they are hoping that they are able to make a reasonable profit. They have to recoup the costs of developing each drug (including the ones that failed before getting to market). And to satisfy shareholders, they try to make as much profit as they can.

The amount that Pharma charges is based on a variety of factors, but you're right that it is largely what the market will bear in the presence competing drugs. For a cancer drug, the amount is whatever the insurance companies will pay. And that amount is always negotiated. The market will determine what is reasonable.

However, they still have a giant research and development machine that must be financed. If they aren't making enough on their current drug lineup, a company either needs to charge higher prices or slim down their drug development pipeline.


Yes that's all I've been saying. So sure, the future pipeline gets slimmed because of lowered expected returns.

There might even be further decreases to productivity of the research pipeline due to economies of scale (investigating one drug may make you stumble on a cure for something you weren't even looking for). Or there might be significant diminishing returns to more pharm industry research, because of the dependence on advances that only come through basic biology research. So it is hard to say which outcome is optimal.

Nothing in economics says that the money generated through monopoly prices due to patents is an optimal amount for drug research and development. And why chose 20-year patent terms rather than 30? Or 10? It's just kind of a system we've thrown together haphazardly.

Through NIH we fund more than half of drug research and basic biology research largely outside of the patent system. India funds research as well that we take advantage of, and India provides the early education for a very significant proportion of our graduate-student/pharm-industry-researcher population.

In practice, any monopoly (which is what patents provide, though in reality upwards of 20% of pharm research is just wasted on researching patent workaround processes and drugs to break the monopolies of competitors, adding no new functionality) will try and price discriminate. E.g. low-income people can get coupons for prescription drugs in the US and pay way less than high-income people, though it will be less relevant once we have near universal insurance coverage.

So, in the presence of patents and import/export restrictions/tariffs, the companies would end up charging much less on average per-pill in India and other low-wage countries than in the US in order to maximize profit. This means that though we give India a subsidy, it doesn't cost us much in lost revenue relative to the number of people in India who get a benefit.


> This starts to get murky from an ethical point of view because we are talking about a cancer medication, and I doubt that software IP would fall under the compulsory licensing. But, cancer drugs are expensive to develop. Bayer should absolutely be afforded some IP protection to recoup the costs of developing the drug. Otherwise, they'll just stop; or more likely, just increase the prices elsewhere around the world.

If they wanted to make money in the Indian market and be afforded IP protection, they could've priced the drug reasonably. Surely a smaller profit is better than no profit?


That Indian generic sold elsewhere would be subject to patent licenses active elsewhere, payable to Bayer. If people try to get it across borders without paying the license, customs are generally quite helpful with collecting such contraband.


Dying of cancer is more expensive than developing a cure, if you're ethical and think life is more important than money.




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