Ah, yes. I think with my machine being a very old model (MBP 4,1) there was some issue for why I didn't do this. Perhaps the maximum speed of the optical bay? I'll have to look up the specs again to see if it wouldn't be worth the trade off, as it would be great to make the old goat more portable. Thanks for the tip!
My original SSD setup didn't actually have any problems in the 2007 model MacBook Pro, so I can't imagine you would either. The speedup is absolutely incredible, even with a cheap Chinese SSD.