Or maybe after all the topical I used, enough was absorbed that in effect I had internal medication. Or, I used enough topical to kill all the fungus in my shoes, socks, etc. so that the next time the nail grew out there wasn't any fungus. It does appear that there was some infection on other nails on the same foot. I never put topical on those other nails, but they have cleaned up, as they have grown out, along with the nail on the big toe that finally grew out healthy.

For a liver, supposedly one of its main roles is to get rid of molecules it doesn't like to see, possibly including anti-fungus molecules.