I would love to have something like the Backblaze client but working with Tarsnap as a backend: you install it and you forget about it. The sensible default configuration is good enough for average joe but you can tweak it if you want.
Well, it is not using Tarsnap as a backend and it seems that you have to add folders on the first launch, that is definitely not what I am looking for :)
Time Machine and Backblaze know how Mac OS is architectured and backup everything but useful files (logs mainly).