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Why do some dimethyl compounds penetrate the skin so easily? Dimethylsulfoxide (DMSO) will even carry various other compounds into the body as well.


DMSO ((CH3)2SO) is a polar aprotic molecule, which means it's neutral _and_ polar. It's easier for a small, neutral polar molecule like DMSO to pass through the phospholipid bilayer of your cells than it is for acetate (CH3COO-).

The "dimethyl" is not what it's important.


My O-Chem teacher had told my about how people who would dissolve hash oil into DMSO to get it across the skin quickly. Usually on their heads.




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