Thanks! Optimization was something I'd played with in previous rounds of coding up AYTO simulations, but not in the most recent version. (See the bottom section of this notebook [0]). There's also a very thorough treatment of the problem in a blog post from 2018 by SAS (the software company) [1]. It's surprising how many people have been drawn in by the allure of AYTO!

[0]: https://github.com/daturkel/pyto/blob/master/AYTO_S8.ipynb [1]: https://blogs.sas.com/content/operations/2018/08/14/are-you-...