One perspective is that the quality and issues of vaccines can vary. Some have more side-effects than others, and some have more issues than others.
Like one specific polio-vaccine that very rarely can mutate into a contagious variant [0]. Or one vaccine for chickens that had some rather serious overall issues [1]. Or that some of the Covid-19 vaccines, hastily developed, were rejected by some countries, while other Covid-19 vaccines were accepted by those same countries.
And vaccines demand a huge amount of trust. Vaccines can be abused in lots of ways by governments, organizations and individuals [2]. This is extra unfortunate, considering the huge potential benefits of some variants of vaccines. Vaccines also require trust in competence and public control [3]. For urgency reasons, standards and checking of vaccines were lowered during the Covid-19 pandemic. Vaccines are also often administered to healthy individuals, not merely sick individuals.
> Because vaccination does not prevent infection with the virus, Marek's is still transmissible from vaccinated flocks to other birds, including the wild bird population. The first Marek's disease vaccine was introduced in 1970. The disease would cause mild paralysis, with the only identifiable lesions being in neural tissue. Mortality of chickens infected with Marek's disease was quite low. Current strains of Marek virus, decades after the first vaccine was introduced, cause lymphoma formation throughout the chicken's body and mortality rates have reached 100% in unvaccinated chickens. The Marek's disease vaccine is a "leaky vaccine", which means that only the symptoms of the disease are prevented.[12] Infection of the host and the transmission of the virus are not inhibited by the vaccine. This contrasts with most other vaccines, where infection of the host is prevented.
Like one specific polio-vaccine that very rarely can mutate into a contagious variant [0]. Or one vaccine for chickens that had some rather serious overall issues [1]. Or that some of the Covid-19 vaccines, hastily developed, were rejected by some countries, while other Covid-19 vaccines were accepted by those same countries.
And vaccines demand a huge amount of trust. Vaccines can be abused in lots of ways by governments, organizations and individuals [2]. This is extra unfortunate, considering the huge potential benefits of some variants of vaccines. Vaccines also require trust in competence and public control [3]. For urgency reasons, standards and checking of vaccines were lowered during the Covid-19 pandemic. Vaccines are also often administered to healthy individuals, not merely sick individuals.
[0]: https://en.wikipedia.org/wiki/Polio_vaccine
[1]: https://en.wikipedia.org/wiki/Marek%27s_disease
> Because vaccination does not prevent infection with the virus, Marek's is still transmissible from vaccinated flocks to other birds, including the wild bird population. The first Marek's disease vaccine was introduced in 1970. The disease would cause mild paralysis, with the only identifiable lesions being in neural tissue. Mortality of chickens infected with Marek's disease was quite low. Current strains of Marek virus, decades after the first vaccine was introduced, cause lymphoma formation throughout the chicken's body and mortality rates have reached 100% in unvaccinated chickens. The Marek's disease vaccine is a "leaky vaccine", which means that only the symptoms of the disease are prevented.[12] Infection of the host and the transmission of the virus are not inhibited by the vaccine. This contrasts with most other vaccines, where infection of the host is prevented.
[2]: https://en.wikipedia.org/wiki/Polio_vaccine
> The fact that the CIA organized a fake vaccination program in 2011 to help find Osama bin Laden is an additional cause of distrust.[120]
[3]: https://en.wikipedia.org/wiki/Cutter_Laboratories#Cutter_inc...