I'm seeing more big botnets hosted on Alibaba Cloud, Huawei Cloud, and one on Tencent Cloud that run Headless Chrome. IP space blocks have been the solution there. I currently have a thread open with Tencent Cloud abuse where they've been begging me to not block them by default.
I don't consider cloud IP blocks a solution. We use Amazon WorkSpaces, and many sites often block or restrict access just because our IPs appear to be from Amazon. There are also a good number of legitimate VPN users that are on cloud IPs.
