People aren't mind readers. If you mean some, don't say whole and you'll probably avoid confusing people.
And overprescribed pain meds are seen as a large cause of it / aggravating factor.
So yeah, "that whole thing". It's not an unusual expression, that I know of.
1- https://en.wikipedia.org/wiki/Opioid_epidemic
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People aren't mind readers. If you mean some, don't say whole and you'll probably avoid confusing people.