I have personal experience with artificial skin products. Someone close to me had a persistent wound on their lower leg that would not heal. Repeated debridement, hyperbaric oxygen, and such didn't get it to heal, but application of patches of a (then new) cultured skin product healed it immediately. Huge QoL improvement.
Was there any specific reason why it wouldn't heal no matter what? Something like diabetes maybe? As far as I know wounds that don't want to heal are pretty rare in people with more or less normal health..