The mobile adapted web interface is pretty good now.

There are already mobile clients for android and, IIRC there were clients for iOS but were banned from the app store due to some kind of infringement (I think it was adult content)

So I don't think a lot of stuff is going to change, excluding the diminishing server load that happened with old clients/extensions.

There already were plenty of ("native") mobile and desktop clients, although they worked by parsing HTML.