It sounds like you're looking for a Django/Rails type framework for JS-- you're not really going to find this. Javascript isn't really the ecosystem that's going to give you something opinionated, although it'd be a nice addition.

I'm not sure you're giving JS it's due. Prisma is an excellent ORM-- it makes Sqlalchemy feel clunky. I'm not sure about your comment on SSR performance either, although I do agree that Vercel tends to be a lot of pixie dust on top of EC2.

What have you used previously?