I finally went back to firefox, recently. I needed to update some of the flag defaults to turn on tab changing with mouse scroll and similar, but they are unlikely to break things like ublock any time soon.
I was a frequent profiles user under chrome, and still don't like firefoxes UI there, but just made a bookmark to the profile launching screen.
You may have reasons to require separate profiles. However, keep in mind that firefox multi-account containers [1] address many of the use cases for separate profiles in chrome with an IMHO better UX.
I finally went back to firefox, recently. I needed to update some of the flag defaults to turn on tab changing with mouse scroll and similar, but they are unlikely to break things like ublock any time soon.
I was a frequent profiles user under chrome, and still don't like firefoxes UI there, but just made a bookmark to the profile launching screen.
It's good enough.