Depends on your schema, really. The hard part is choosing a distribution key to use for sharding- if you've got something like tenant ID that's in most of your queries and big tables, it's pretty easy, but can be a pain otherwise.
For a multi-tenant use case, yeah, pretty close to thinking about partitioning.
For other use cases, there can be big gains from cross-shard queries that you can't really match with partitioning, but that's super use case dependent and not a guaranteed result.
