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If you are willing to share more about your story, I'd love to hear it. Did you cause permanent damage? What were you using and how much? What are the symptoms like now?



Yes, it 100% caused permanent damage in me due to an interaction of the agonist with an unrelated stimulant. After years, I ultimately stumbled upon the combination of memantine+telmisartan which successfully reversed much of the damage. I still have issues with things that I cannot physically tolerate due to the leftover damage. Also, I tried other things like valproate that failed to fully reverse the damage, but caused significant permanent problems of their own. To make a long story short, use gentle safe indirect promoters for NMDA/AMPA like L-glutamine and at most phosphatidylserine, but nothing stronger or more low-level. Leave the direct agonism for the rodent studies.




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