I use Orion a bit on Mac. The blocker for me is that it doesn't support Ublock Origin. They claim that their built in ad blocking does 90% of what you need, but I really just want to be able to remove page elements at will.
This is kind of surprising. For me, uBlock Origin works perfectly on Orion (installed from the Firefox store), and the element zapper / eyedropper in uBlock Origin works as well. I haven't seen any difference between uBlock Origin on Firefox vs Orion.
Orion has a native element remover, just click the paintbrush icon in the toolbar.
uBlock Origin support is at least partial because whenever I click an analytics-redirect link in my email and it opens in Orion, I get a uBlock “tracker blocked” page.
