As someone who has implemented various transport protocols (both standard and custom) the biggest hurdle in layering atop IP will not be the gauntlet of WAN routers, surprisingly, rather consumer NAT devices.
One interesting case for a particular Netgear family of routers was that, while the traffic would survive end-to-end it was not without corruption - very specific corruption which took the form of zeroing the first 4 bytes. Given this aligns with where the src/dst ports would normally be, I suspect it was being treated as TCP/UDP albeit without the actual translation path taken.
One interesting case for a particular Netgear family of routers was that, while the traffic would survive end-to-end it was not without corruption - very specific corruption which took the form of zeroing the first 4 bytes. Given this aligns with where the src/dst ports would normally be, I suspect it was being treated as TCP/UDP albeit without the actual translation path taken.