In my currently opened project I have: vtsls (for typescript), biome, emmet, and the snippets LSP running on the same file.
You can configure which LSPs you can run on a language basis. Globally and per project.
You can also configure the format on save actions the same way. Globally and per project.
I have astro project that on save runs biome for the front-matter part followed by prettier for the rest.