Unless your data-set is highly compressed media files.
In general, even during rsync operations one often turns off compression on large video files, as the compression operation has low or negative impact on storage/transfers while eating ram and cpu power.
De-duplication is good for Virtual Machine OS images, as the majority of the storage cost is a replicated backing image. =3
Compression is still king. Check out HP's Nimble storage arrays. Way quicker to do compression, fewer iops, and less overhead. Even when it misses, like video files, it's still a winner.
In general, even during rsync operations one often turns off compression on large video files, as the compression operation has low or negative impact on storage/transfers while eating ram and cpu power.
De-duplication is good for Virtual Machine OS images, as the majority of the storage cost is a replicated backing image. =3