I know virtually nothing about Mr Beast other than that he's massively successful due to dumb videos that apparently raise lots of ethical questions.

That's not an endeavor I'd be interested in participating in, but I did find the PDF fascinating and read all of it.

A good bit of his guide is about 1. taking responsibility for delivering what you are expected to 2. keeping the big picture in mind

Plenty of folks could benefit from that advice and the examples he provides to make it more concrete.