I want to mention an interesting industrial enzyme project. If you ever saw the laundry detergent commercial "Protein gets out protein", this is referring to an industrial enzyme in laundry detergent. Many years ago, Genentech had built up a significant capability in proteases, which are proteins that cut other proteins into pieces. In the course of optimizing proteases, they made a thermostable, thermoactive protease. Although it wasn't super useful for Genentech in a drug discovery context, it was recognized that you could put an inactive enzyme into laundry detergent that would be activated when the hot laundry water hit the detergent, and the resulting protease would be good at cleaning stains (many stains are composed of protein- blood, food, etc).

Genentech set up a subsidiary with Corning (the glass company) that owns the IP for this protease and then licensed it to laundry detergent manufacturers; many billions of dollars in revenue. I think this is one of the original patents: https://patentimages.storage.googleapis.com/d9/ca/6f/2fb89ff...