It depends on what you work with. If you debug a complex issue you need to check many different setups to see whether your suspicions are right. Then, having a nice workflow where you sticky edit and run your code is quite important.

It's not always the case. Quite often the only way to investigate the issue is to run a cloud workload that takes several minutes to start. Still, if you write good code, you can try to isolate the issue for local debugging at some point.