Felix's upcoming work is intriguing and would enable a much nicer integration of Python into the Excel ecosystem. The use of PyOdide and WASM enables execution of the Python logic on-device. The same tactic is used by PySheets and taken a bit more to the extreme by implementing the cell functions, but also the entire sheet UI and logic in Python. Check it out if you are approaching the space from the perspective of a Python programmer, rather than an Excel user. See https://pysheets.app