Maybe professional bias but I prefer to follow a cattle vs pets approach here and treat them as disposable, meaning: let the sd card break and optimize for quick replacement.
NVMe SSDs cost the same as SD cards nowadays. You can treat the SSDs as disposable if you want, but you are going to quickly realize that this mindset isn't exactly actionable, because there is nothing that needs disposing of.
Current Pi 4s & 5s support booting from USB out of the box with no configuration (took them long enough), so I don't think it's worth the downtime and wasted SD cards.
