Yes they are compatible as long you use actions available on both platforms. For example, you can use AppleScript or shell in macOS but it will not work on iOS. However, if you use cross platform apps shortcuts it works even when you write files into the iCloud folder. For example, I did a shortcut that takes today’s events from the Calendar and appends the list into a Markdown file in a Obsidian vault on iCloud. I use it to scaffold meeting notes, and it works on my phone too.