Sure, but it doesn't have the same functionality [1]:
> With Manifest V3, uBlock is required to limit how many websites our users are able to add to their allow lists. Going forward, you'll only be able to add up to 5,000 websites to your allow lists.
> Moving forward, we’ll no longer be able to enable automatic daily updates to filter lists.
> With Manifest V3, uBlock is required to limit how many websites our users are able to add to their allow lists. Going forward, you'll only be able to add up to 5,000 websites to your allow lists.
> Moving forward, we’ll no longer be able to enable automatic daily updates to filter lists.
[1] https://support.ublock.org/hc/en-us/articles/11749958544275-...