> You could sum up Alzheimer's as: Diet/Lifestyle + a congenital form of Cushing's syndrome and you have increasing glucocorticoids which imply downregulation of the PVN,
Between weight loss, inhibiting addictive behavior, lowering the risk of major cardiovascular events such as stroke, heart attack, and potentially derisking for Alzheimer’s, we should be pumping GLP-1 agonists out like a wartime effort. Likely contributor to fixing 70+ years of socioeconomic configuration that gave us Western Disease and the trimmings that come with it.
Wit all else patients on GLP-1 agonists I wonder if the incidence of Alzheimer’s will decline? I wonder if Semaglutide reduces CRP? There are some preliminary indications that it may: https://cardiab.biomedcentral.com/articles/10.1186/s12933-02...