I don't watch many movies but in the ending of the Spiderman video game (Spoilers:) there is a deadly virus going around and aunt May is on her deathbed from it. Spiderman gets just enough antiserum to save her or to study it and make more but she will not live long enough for that. It's an emotional scene and they don't weasel out of it by having her decide for him, or giving some signs that she wouldn't make it. He ultimately gives the vial to a doctor and the scene fades as he is crying on his knees over aunt May in her hospital bed.

https://youtu.be/Q3hAt1uWo8M?si=7JdVISScles5PPKD