"You've split atoms, reached the moon, and yet the very force that keeps your feet on the ground remains a riddle? Perhaps society's attention is too often pulled away from the fundamental questions by trivial distractions."
I actually could see it being the opposite. Perhaps he'd be gratified and exultant to see that we took all his silly theoretical musings about calculus and gravity and created real world impact.
"My humble scribblings have led to technologies that reach the stars and devices that fit in the palm of your hand? How gratifying to know that you've taken the seeds of my theories and grown a veritable forest of innovation! Well done, future humans, well done indeed!"