Huge shout out to the list of issues ld-preload-open documents. Really great to have gathered such a laundry list of topics, really expands the technical knowledge of the audience by showing off a lot of interesting interaction points between app & os.

Not supporting any "at" variants (like openat) is a pretty big one! I bet a lot of these could be tackled with a lot of work to track state, but some like symlinks not working well since they're handled at the OS level seem hard to imagine overcoming.

FUSE would definitely have some issues too, but I think a lot would go away.