Having used Node/express, Rails, Flask, and Django extensively, I have been very impressed with Django. The framework itself is good, but the superpowers come from the ORM and DRF, and a few other great plugins. The stuff you can do with the ORM and DRF is nothing short of incredible. Now, you could argue that the framework shouldn't be tightly coupled to the ORM, and sqlalchemy does provide some stiff competition as an example of that, but in my experience Django ORM edges out sqlalchemy in terms of usability.

There are some footguns around N+1 queries, but they are general to all database interfaces and pretty easy to avoid IMO.