I love my Duo 2 (after doing a ton of ADB `pm disable-user com.[microsoft|google].shitware` lol) and will definitely try this out once it's better supported.
Do you mean sufficient to truly disable unwanted applications? As far as I know `pm disable-user` is as good as using the "Disable" butan in the app manager GUI, except `pm` works for some packages where the GUI option is greyed-out: https://www.xda-developers.com/disable-system-app-bloatware-...
I get most of my apps from F-Droid, and I use Aurora Store or just temporarily re-enable the two Google Play packages to install/update apps from there. Here's what I was left with after disabling all the trash, after installing one (1) Play Store app, but before installing everything else from F-Droid: https://i.imgur.com/yHIrm3u.png