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Dehydration and kidney damage is a common side effect of Semaglutide, and they regularly test for that if you are on it. Drinking plenty of water is the way to prevent that from happening.


Perhaps I misunderstood what the GP was asking. Nevertheless GLP-1 medications appear to be kidney protective from a long term standpoint with an increased short term risk of AKI likely primarily related to GI losses with additional risk conveyed by concomitant use of “depleting” (diuretics) and nephrotoxic meds. Once on a stable dose there’s no current recommendation to monitor kidney function beyond what would normally be indicated for diabetes (usually yearly).




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