I'm not sure that "lean start-up" and "self-replicating, consuming machines" go well together. I mean, the competition has had a 3.9 billion year[1] head-start. Considering the number of algorithmic mistakes[2] made specifically involving consume + replicate features of products purchased from the current leader in the industry, I'd prefer to see that done on a slower timeline. Perhaps some careful decades of engineering are called for. Same goes for "making and inserting DNA sequences at your desk for under $1,000."
...I'm pretty sure you're not going to save much mass by soaking in a year of sunlight...