You can commit line by line within Github Desktop and its a much nicer experience IMO than doing so via CLI. Its much easier to jump around to different files and commit related line changes in a bigger PR than jumping in and out of the patch command.
It's been a while since I've tolerated the git gui interface, but when I used to use it, the line-to-chunk logic would regularly fail on short 2-3 line spans.
There's a stackoverflow discussion [1] that suggests it was fixed in 2018, but for many years it was a terrible experience that pushed me to use other frontends just for reliable partial staging.
