It'd depend on the field (and region), I imagine, but after the first job or two I feel like all that matters with respect to schooling is that you went. Five or ten years into a career I'd be surprised if coursework that hadn't been used on the job was relevant, and GPA wouldn't even be considered.
Hobbies are probably not that useful either, but I could see them catching a hiring manager's eye. Coursework probably won't have the same effect, although I suppose it could help you get through ATS.
Not that I think anyone's really looked at my resume for over 20 years (jobs through network), but I think the idea of a hobbies line is that it can be a conversation ice-breaker. That said, I don't think I have one on mine. If theey Google me they'll turn up more than enough to talk about.
Hobbies are probably not that useful either, but I could see them catching a hiring manager's eye. Coursework probably won't have the same effect, although I suppose it could help you get through ATS.