No. This a tiny change in O2 concentration.

Tiny changes could be relevant, especially over time, no?

Over like 10,000 years this rate of change would matter, but since this seems to be related to binding O2 into CO2 and H2O due to burning fossil fuels, increased CO2 over 10,000 years would cause world shattering effects before we continue to cause it for 10,000 years. Also we would probably run out of fuels before the O2 concentration becomes an issue.

Interesting to think about... I wonder if there would be a snowball effect of O2 loss with losing vegetation on land and in sea, having an effect as temperatures rise.