It works both ways - a CEO throwing out resumes with prejudice means the candidate doesn't have to suffer a prejudiced CEO, "big boy company" already says a lot about the culture you're trying to foster.
Well put. There’s the adage that says don’t judge people as you have literally no idea what they might be going through. In this case you have no idea why they did a stint in crypto. Now, if during an interview it’s clear that someone has a strong ideological connection to crypto (or anything really), and you want to foster more of a “make it work“ engineering culture, then by all means don’t offer the position. Excluding people based on whims like this will not set your company up for success.
Crypto people and big company people are not distinct groups. You can find people that worked in large and small companies that never touched crypto, but also find people who worked in large crypto. Coinbase is a great example, as with their 6k+ peak employees count they definitely were are larger company.