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I'm confused - nothing at Neuralink is off the shelf. How would you go from an empty room to an animal implanted functionally with lots of data?



What is there to be confused about?

On the one hand you seem to be arguing that neuralink is more complicated and has more unknowns, and that this explains why it needs to do more animal tests, but that depends on how much data one can capture in a single test. So it is not a given that the complexity-to-tests-needed graph is linear.

And assuming that we do actually capture a lot more data in a single test (I would hope so at least), then that also means more work needs to be done to interpret this data in a meaningful way and make improvements. Which would suggest that it should take more time to move on from one test to the next.

There is a difference between total animal tests and how quickly the tests are done.


One of the example applications proposes to stimulate patterns of neurons in visual cortex to produce vision. To even get to the point where you can train a monkey to detect phosphenes, Neuralink had to (a) develop a way of producing flexible electrodes that would measure activity from a single neuron, were robust enough to be implanted, would survive the punishing in-vivo environment, and retain their ability to measure and stimulate for long periods of time (none of those steps can be adequately done in in vitro models). (b) They then had to make sure that their robot could implant them to the proper depth (despite brain movement), and that during implantation they could maintain connection to the interface system. (c) They had to build a ASIC that would capture a 1000 of channels of neural data and wirelessly transmit them, while ensuring that the SNR was sufficient for use (again, no in vitro model). (d) They had to test the encapsulation of the ASIC to make sure that it, too, could survive in vivo.

They could certainly have done all these things serially, but it would have taken a lot longer. In the end, where they are is still far from a useful product - they have monkeys that can see phosphenes, they have electrodes that last 1 year, and they have a reasonable ASIC - but compared to the academic timescale, where we've been working on these individual pieces 1 PhD (6 years) at a time, they've made really remarkable progress.


It's amazing that we expect them to ever get that all right when they screw up what glue to use.




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