You can, but it's impractical (operationally and in tx costs) as it requires a live bot to constantly adjust margin between the exchange and the self-custody wallet, due to the way typical crypto trading products work: at max margin, the chance of liquidation is too high, not so much because of liquidation itself (that can be risk managed and averaged out) but due to the enormous implied fees associated with liquidations. Example pricing: bet 5 at max leverage, lose 2 due to market movements, the account is zeroed aka liquidation fee of 3.