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For polygenic traits no, it hasnt been out of the box long enough for the embryos to mature.

However, we have been screening for single gene mutations that impact IQ since the the 1960s and they are well validated. For example, the impact on IQ of Trisomy 21 (downs syndrome) has a well validated impact of about 30 IQ points. 16p11.2 Gene abnormality has a well studied impact of 16-25 IQ points depending on the abnormality.

If you had a dumb as rocks polygenic test that screened just these factors, you would see a noticeable difference compared to a control.




How many generations does it take before the test fails due to Goodhart's law?




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