Hacker Newsnew | past | comments | ask | show | jobs | submitlogin

I would think that any positive effect could be reversed by essentially giving the opposite. Want to decrease inflammation? Get a younger gut biome. Mess up and get an older gut biome and you probably end up with increased inflammation.

There is also evidence that fecal transplant recipients take on physical and mental traits of the donor.

Quoting from https://www.abc.net.au/news/2017-05-09/faecal-transplant-sid....

"There have been people who have taken on the shape of the donor, such as if the donor is either overweight or underweight they've become more like that."

"There's even been reports of some people who have never been depressed getting a transplant from someone who's had depression and ending up with their first episode of depression after that."



Without robust statistical evidence these kinds of reports seem very prone to confirmation bias or placebo effect.


Yeah. I have an annoying, but not debilitating autoimmune disease. I’ve read case studies of people who got a FMT for other reasons (fixing gut infection in hospital) who have the same disease but much worse having massive reductions in symptoms for years. I think maybe there are some RCTs happening now for it but I think they still have some years to run.

But yeah, reading the stories like what you linked is why I am very wary - I really want to be able to get a prepared mix of isolated, cultured, known good bacteria that can be inserted in to just seed some more of the good stuff. I think that removes a lot more of the ‘ick’ factor (even if the bacteria strains were originally isolated from faecal samples) even though what I have is bad enough that I would totally do a normal FMT if I thought it was safe enough!


So i need to find someone who's fit, normal weight, and happy and steal their poop?


Step one start johnslist.

Step two pretend to be a 6'6" Olympian fit to leave 100 years and die a barely aged god with great hair in Indiana Jonesque adventure.

Step three omitted for grossness.

Step four profit!


South Park satirized this, where Tom Brady’s stool was treated just like the Spice from Dune.


Theft is often unethical; you could simply buy the poop.




Guidelines | FAQ | Lists | API | Security | Legal | Apply to YC | Contact

Search: