The first of those papers (mostly about a different drug with similar pharmacokinetics) is a review paper mostly about experiments on rats, though it does also include some results on ADHD patients, and the second one is a meta-analysis of 48 experiments, specifically excluding experiments on ADHD patients.

It's not literally false that "the studies specifically refer to ADHD patients", because they do refer to them in order to explain that the results they're reporting are not in ADHD patients—in the first case, primarily; in the second case, at all. But your comment is crafted to create the false implication that their results were limited to ADHD patients. Either that is a knowing lie, or your claim to have scanned the papers is a knowing lie and your false implication is merely reckless disregard for the truth.

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The first study you said you scanned, Spencer, Devilbiss, and Berridge 2015, is about the effects of amphetamines and methylphenidate in rats and healthy people, and how that relates to their usefulness for treating ADHD:

> A major breakthrough in our understanding of psychostimulant action was the demonstration in 1980 that the cognition-enhancing and behavioral-calming actions of psychostimulants are not unique to ADHD, with similar effects seen in healthy human subjects (11).

> This and subsequent studies unambiguously demonstrate that when used at low and clinically-relevant doses, psychostimulants improve prefrontal cortex (PFC)-dependent behavioral/cognitive processes in human subjects with and without ADHD (11-15).

In the summary, it concludes:

> Low-dose psychostimulants are the first-line treatment for ADHD. At clinically-relevant doses these drugs improve frontostriatal cognitive function in ADHD patients and healthy individuals.

> The procognitive and behavioral calming actions of psychostimulants are in stark contrast to the behaviorally-activating and cognition-impairing effects seen with higher doses.

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The second study, Ilieva, Hook, and Farah 2015, is titled, "Prescription Stimulants' Effects on Healthy Inhibitory Control, ...A Meta-analysis." Here "healthy" means neurotypical, i.e., not "mentally ill," specifically including ADHD diagnoses as "mentally ill" and excluding them from "healthy". They explain, "Research on children, elderly, criminal, or mentally ill patients was excluded," elaborating, "Twelve studies failed to meet the criteria for eligible participants (mice: n = 1; elderly participants: n = 6; children: n = 2; mentally ill participants: n = 2, including one study on ADHD and one study on cocaine abuse; criminal participants: n = 1)."

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In short, you are telling baldfaced lies about the studies I'm citing, as easily shown by the most cursory analysis (in the second case, the title of the paper), in order to continue posting vile calumnies against my integrity.

I do not think you should post any more on this site.

Perhaps you should...relax. You and the person you're responding to are having a miscommunication. It happens. No one is making any statement about your integrity.

Also, perhaps you should take a better look at the comment tree. My original request for a citation was levied against the commenter speculating that "this was made up to stop it from getting banned entirely like it is in Asia"

So really, maybe go get some fresh air. It's just a discussion on the internet, it's not worth getting worked up over.

> No one is making any statement about your integrity.

That is not correct; in https://news.ycombinator.com/item?id=31231494 luckydata said, "I think you're purposefully misrepresenting...", and in https://news.ycombinator.com/item?id=31241664 they said, "I'm even more convinced now than before that you're in bad faith." Decent people considering commenting on here should not have to worry that they'll be subjected to such character assassination.

(And neither should I.)

Thank you for clarifying your comment. I think the Spencer et al. paper shows that it wasn't made up to stop Adderall from getting banned entirely; rather, it was a belief that was common among researchers in the field until 40 years ago, based on clinical observation. Also, Adderall is not banned entirely in Asia; for example, last I heard, it's legal in Thailand.