>Pyroptosis is a series of biochemical reactions that uses gasdermin, a protein, to open large pores in the cell membrane and destabilize the cell.
> They discovered that certain conditions, like specific concentrations of calcium ions, for example, triggered the pores to close within only tens of seconds.
They dont say what specific calcium concentrations are in comparison to normal concentrations, but ageing and a variety of diseases are linked to calcium & phosphorus (phosphate) build up in a variety of organs.
So the question is, is calcium a silent killer or delaying the inevitable?
Considering K1 is taken up by many cells extremely quickly into the Rough Endoplasmic Reticulum, I wonder how that alters this experiment?
> They discovered that certain conditions, like specific concentrations of calcium ions, for example, triggered the pores to close within only tens of seconds.
They dont say what specific calcium concentrations are in comparison to normal concentrations, but ageing and a variety of diseases are linked to calcium & phosphorus (phosphate) build up in a variety of organs.
So the question is, is calcium a silent killer or delaying the inevitable?
Considering K1 is taken up by many cells extremely quickly into the Rough Endoplasmic Reticulum, I wonder how that alters this experiment?