Re: mini itx cases, I'm surprised no one is mentioning the meshlicious case[1] (linking to Newegg because ssupd's website seems to always be so slow). The nice thing about this case is that it comes with a pcie riser allowing for some pretty large GPUs to fit in it.
Just did two builds in this case and absolutely love it! Re:Hair/dust, the side panels are so easy to remove that it's been no problem to just hit it with a duster every once in a while. It's small enough to easily take outside for a cleaning, compared to the effort needed to clean my full tower.
Interesting design! But I have to wonder how well it works in places with hairy animals in them, or places that have more dust than general (older buildings, exposed "hipster" walls and on so on). Cleaning the inside of the PC once a year would probably not be enough anymore.
[1] https://www.newegg.com/black-ssupd-meshlicious-mini-itx/p/2A...