From a practical point of view, the only thing it broke was Ad sponsored results on Google, so I had to teach my wife to go for the normal results, or search directly on Amazon or Wayfair or wherever. What broke for your wife's online shopping?
You're not alone. I took out my partner's online calendar by mistake with a PiHole. I think I blocked all her productivity SaaS tools too. Found out in under 5 minutes.
My dad had an outdoorsy distribution list that shoved all links through an ad domain, like straight up as if it was clicked on a site. He was able to copy and paste the text just fine...