Could design a website that was the equivalent of "imagine coming home and finding somebody had removed every switch, button and lever from every device in your environment; What would you do?"

i.e. where "able-bodied" visitors would have to figure out how to interact with the site without all their usual means.

If you designed it right and maybe even gamified it (in a good way that doesn't trivialize, that challenges you to learn), it might entice young and old to explore what it means to have to interact with the world without the benefit of X.